Is Fibromyalgia Due to a Neurontin or Lyrica Deficiency?


(updated January 2024)

Neurontin (Gabapentin) like its kissing cousin Lyrica (pregabalin) are antiepileptic drugs commonly used for treating neuropathic pain, usually defined as pain due to damage to nerves. This would include post herpetic neuralgia (persistent pain experienced in an area previously affected by shingles), painful complications of diabetes, nerve injury pain, phantom limb pain, fibromyalgia and trigeminal neuralgia.

The studies released on these meds by the drugs manufacturer, Pfizer, should be, like most self-funded research, taken with a grain of salt.
Harvard Medical School’s Dr. Marcia Angell is the author of The Truth About the Drug Companies: How They Deceive Us and What to Do About It. But more to the point, she’s also the former Editor-in-Chief at the New England Journal of Medicine, arguably one of the most respected medical journals on earth. But after reading her article in the New York Review of Books called Drug Companies & Doctors: A Story of Corruption, one wonders if any medical journal on earth is worth anybody’s respect anymore.
“It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine.”

So when we see the research studies as the one below, please keep in mind we are getting the best case results and mostly likely a very different view than the true picture of what this or that drug REALLY does or doesn’t do.

The Research on Gabapentin Reports –
This review looked at evidence from 29 studies involving 3571 participants.
file1801281015946In people with these conditions, gabapentin is associated with a moderate benefit (equivalent to at least 30% pain relief) in almost one in two patients (43%), and a substantial benefit (equivalent to at least 50% pain relief) in almost one in three (31%).
Over half of those taking gabapentin or pregabalin for neuropathic pain will not have good pain relief, in common with most chronic pain conditions. Adverse events are experienced by about two-thirds of people taking gabapentin, mainly dizziness, somnolence (sleepiness), edema (swelling), weight gain, depression, poor memory, incoordination, fatigue, and gait disturbance.
It’s no secret I’m not a fan of either of these drugs. I firmly believe they cause more harm than good. However, I’m a realist and know there are patients who benefit from these drugs, but for most the benefit comes at a cost, life draining side effects. One third of patients or a little 3 out of 9 will see a benefit, the rest will not. Doctors desperate to help their patients with fibromyalgia are happy to drink the purple Kool-Aid and buy the propaganda churned out by Pfizer.
However, soon enough doctors are confronted with fibro patients who report that this drug like the other drugs, isn’t helping. Doctors become disgruntled and start to suspect their patients are hypochondriacs or worse pill seekers.
Patients can’t help the fact they are one of the 2/3 of patients that Lyrica or Neurontin, doesn’t help. Or they are one of the many who simply can’t tolerate the drugs side effects.
Unfortunately, traditional medicine focuses on treating symptoms, not causes. With so many symptoms, often unexplained symptoms, fibro patients are at risk of being on multiple drugs, each treating one of the many symptoms. Eventually patients are taking a half a dozen or dozen drugs not knowing which if any are helpful, or just as importantly which are harmful, it becomes muddied.
Dr. Rodger Murphree's Fibro Doctor: What is Your WHYPatients often forget what they are taking the drugs are for… Even worse are doctors who gloss over a patients chart and don’t bother to do the detective work to figure out if in fact a drug is causing a side effect, contributing to their overall poor health, or if the drug is even needed. This is common with complicated patients who are in desperate need of feeling better who continually visit by doctors whose only tool to help them is the prescription pad.
I spend a considerable amount of time helping my patients sift through which if any of their drugs is helping, most are not. It is not uncommon to have patients who are taking a dozen drugs when they start working with me. Most are able to drastically reduce or totally eliminate these drugs, finding that many where actually causing more harm than good.
It may surprise you to learn that one of the potential side effects for both Neurontin and Lyrica is diffuse achy pain. Yes pain! I’ve had numerous patients wean off these drugs and discover that low and behold their pain has actually improved. Imagine that.
We are told that there are new and improved drugs on the horizon for fibromyalgia. I’ve already written about many of these drugs. I’m not optimistic.
After specializing in treating fibromyalgia for the last 18 years I firmly believe they only way to beat this chronic illness is to get healthy. Drugs don’t make you healthy, never will. They can be helpful, sometimes life saving, but the body will always perceive them as foreign invaders which eventually increase the risk of life robbing side effects.
Finding and correcting the cause(s) of your fibromyalgia symptoms should be the goal. Drugs if needed, should be used short term to manage symptoms while focusing on correcting the causes of fibromyalgia, adrenal fatigue, low thyroid, bankrupted stress coping chemicals, depleted essential vitamins, minerals, amino acids, and hormones.  

These patients and hundreds of others who’ve worked personally with me have in fact beaten their fibromyalgia. You can read or listen to their stories by clicking the link below:


Cynthia's Story

Janna's Story


Robin's Story


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