Inflammation linked to Alzheimer’s Disease

Alzheimer’s disease is a progressive and fatal brain disease that affects some 5.3 million Americans. Over the past 25 years, the number of patients who have Alzheimer’s disease has doubled, and the incidence is expected to increase in coming decades as the US population ages. It’s now become the sixth-leading cause of death in the United States. The disease destroys brain cells, causing problems with memory, thinking, and normal behavior.

The disease typically begins with moments of forgetfulness, or memory lapses. People afflicted with Alzheimer’s gradually lose cognitive ability as their neurons (brain cells) are attacked and destroyed.

As the disease advances, words are forgotten, and the person’s mental abilities become severely compromised. In the final stages, the person may no longer be able to dress, eat, or perform simple tasks. Loss of judgment and reasoning occurs. Delusions are common.


Evidence linking inflammation and oxidative stress to Alzheimer’s disease continues to grow. Research shows that inflammatory chemicals, known as cytokines attack the brain chemicals of those with Alzheimer’s. Cytokines set-off inflammatory reactions, generating high levels of free radicals. The free radicals lead to the formation of beta-amyloid plaques. This results in more inflammation, free radicals, and more destructive beta-amyloid plaques.  Reducing inflammation & resultant free radical formation is the key to reducing the risk of, and helping to reverse, the damage of Alzheimer’s disease.

 

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There’s emerging research that also links chronic inflammation to allergies, asthma, Alzheimer’s disease, cancer, diabetes, digestive disorders, heart disease, hormonal imbalance, strokes, heart attacks, arteriosclerosis, and osteoporosis…

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